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Indirect Genetic Effects: A Cross-disciplinary Perspective on Empirical Studies
Amelie Baud1,2, Sarah McPeek3, Nancy Chen4
1Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
The Journal of Heredity
|October 13, 2021
Summary
Indirect genetic effects (IGE) occur when genes in one individual influence another
Area of Science:
- Genetics
- Evolutionary Biology
- Behavioral Genetics
Background:
- Indirect genetic effects (IGE) arise from genetic variation in conspecifics influencing an individual's phenotype.
- IGE are crucial in behavioral, evolutionary, agricultural, and biomedical genetics.
- Empirical study of IGE lags behind theoretical development due to measurement challenges.
Purpose of the Study:
- To identify challenges in measuring and understanding IGE.
- To propose solutions for overcoming these empirical hurdles.
- To highlight the importance of conspecific interactions in biological systems.
Main Methods:
- Review of current challenges in IGE measurement.
- Cross-disciplinary examples from evolutionary, agricultural, and biomedical genetics.
- Focus on solutions leveraging genomic, monitoring, and phenotyping technologies.
Main Results:
- Identified significant pitfalls in deconvoluting IGE from direct genetic effects.
- Highlighted the ubiquitous nature and profound implications of IGE.
- Showcased how technological advancements can facilitate IGE research.
Conclusions:
- Addressing measurement challenges is key to advancing IGE research.
- Technological innovations offer promising avenues for empirical IGE studies.
- Understanding IGE is essential for a comprehensive view of biological interactions.
Keywords:
dynastic effectgenetic nurtureindirect genetic effectinteracting phenotypesneighbor effectsocial genetic effectMore Related Videos
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