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Updated: Oct 17, 2025

Author Spotlight: Assessment of Visual Acuity in Central Vision Loss Through Motion-Based Peripheral Vision Testing
Published on: February 23, 2024
Suppression of motion vision during course-changing, but not course-stabilizing, navigational turns
Lisa M Fenk1, Anmo J Kim2, Gaby Maimon3
1Laboratory of Integrative Brain Function and Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA; Active Sensing, Max Plank Institute of Neurobiology, Martinsried, Germany.
Abstract:
From mammals to insects, locomotion has been shown to strongly modulate visual-system physiology. Does the manner in which a locomotor act is initiated change the modulation observed? We performed patch-clamp recordings from motion-sensitive visual neurons in tethered, flying Drosophila. We observed motor-related signals in flies performing flight turns in rapid response to looming discs and also during spontaneous turns, but motor-related signals were weak or non-existent in the context of turns made in response to brief pulses of unidirectional visual motion (i.e., optomotor responses). Thus, the act of a locomotor turn is variably associated with modulation of visual processing. These results can be understood via the following principle: suppress visual responses during course-changing, but not course-stabilizing, navigational turns. This principle is likely to apply broadly-even to mammals-whenever visual cells whose activity helps to stabilize a locomotor trajectory or the visual gaze angle are targeted for motor modulation.
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