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Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Updated: Oct 17, 2025

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

Equine Cutaneous Lymphoma: A Case Report.

Janet D Littlewood^1,2, Katherine E Whitwell², Michael J Day³

¹*Centre for Small Animal Studies, Animal Health Trust, P.O. Box 5, Newmarket, Suffolk CB8 7DW, U.K.

Veterinary Dermatology

|October 14, 2021

Summary

This summary is machine-generated.

This study describes a 15-year-old horse with cutaneous lymphoma, characterized by T-lymphocytes. Treatment with intralesional glucocorticoids and oral progestins led to complete resolution of the nodules.

Keywords:

Histopathology Horse Immunohistochemistry Lymphoma Skin diseases

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Area of Science:

Veterinary Medicine
Oncology
Immunohistochemistry

Background:

Cutaneous lymphoma in horses presents a diagnostic challenge.
Long-standing cases require thorough histopathological and immunophenotypic evaluation.

Observation:

A 15-year-old mare presented with a decade-long history of multiple cutaneous nodules.
Histological examination of biopsies taken four years apart confirmed cutaneous lymphoma.
Immunohistochemical staining identified the neoplastic cells as T-lymphocytes.

Findings:

This case represents the first immunophenotypic characterization of equine cutaneous lymphoma.
The identified T-lymphocyte lineage provides crucial information for understanding the disease.

Implications:

The findings contribute to the understanding of equine lymphoma subtypes.
Successful treatment with intralesional glucocorticoids and oral progestins offers a therapeutic option.
This case highlights the importance of advanced diagnostic techniques in equine oncology.