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Updated: Oct 17, 2025

Isolation of Small Preantral Follicles from the Bovine Ovary Using a Combination of Fragmentation, Homogenization, and Serial Filtration
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Follicular dysplasia in two cows.

Mansell1

  • 1Texas Veterinary Medical Diagnostic Laboratory, PO Box 3040, College Station, TX 77841, USA.

Veterinary Dermatology
|October 14, 2021
PubMed
Summary

This study details follicular dysplasia with pigmentary changes in two adult cattle, characterized by hair loss and melanin clumping. The findings expand understanding of this rare cattle syndrome.

Area of Science:

  • Veterinary Dermatology
  • Animal Pathology

Background:

  • Follicular dysplasia is a rare condition affecting cattle hair follicles.
  • Pigmentary changes associated with follicular dysplasia are infrequently reported.

Purpose of the Study:

  • To describe the histological features of follicular dysplasia with pigmentary changes in two adult cattle.
  • To contribute to the understanding of this uncommon syndrome in cattle.

Main Methods:

  • Histological examination of skin biopsies from affected cattle.
  • Clinical observation of affected animals.

Main Results:

  • Two adult cattle (Brangus-cross and Angus) presented with adult-onset diffuse alopecia.
  • Skin biopsies revealed follicular distortion, atrophy, and melanin clumping within follicular epithelium, matrix cells, hair shafts, and infundibular keratin.
Keywords:
alopeciabovinecattlefollicular dysplasiaskin

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  • Affected animals were otherwise clinically normal.

    • Conclusions:

    • The histological findings confirm and expand upon the infrequent reports of follicular dysplasia with pigmentary changes in cattle.
    • This syndrome presents as alopecia with characteristic melanin clumping in hair structures.