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Topical treatment of canine and feline pyoderma
1Clin. Vét. Saint Bernard, 598 Avenue de Dunkerque, 59160 Lomme, France.
Abstract:
Abstract This paper is a review of commonly used topical antibacterial medications: benzoyl peroxide, chlorhexidine, povidone iodine, ethyl lactate, triclosan, mupirocin, neomycin, polymyxin B, bacitracin and fusidic acid. Included is a review of the pharmacokinetics, modes of action, adverse effects and clinical uses in veterinary dermatology. General recommendations for topical antibacterial therapy are presented. Résumé- Cet article est une revue des topiques antibactériens les plus couramment utilisés: peroxyde de benzoyle, chlorhexidine, povidone iodée, lactate d'éthyle, triclosan, mupirocine, néomycine, polymyxine B, bacitracine et acide fucidique. Il inclut notamment une revue des pharmacocinétiques, des modes d'action, des effets secondaires et des indications thérapeutiques de ces produits en dermatologie vétérinaire. Les indications générales du traitement topique antibactérien sont présentées. [Guaguere, E. Topical treatment of canine and feline pyoderma. (Traitement topique des pyodermites canines et félines). Veterinary Dermatology 1996; 7: 145-151.] Resumen Este articulo es una revisión de los productos tópicos antibacterianos más frecuentemente utilizados: peróxido de benzoilo, clorhexidina, povidona yodada, etillactato, triclosan, mupirocina, neomicina, polimixina B, bacitracina y ácido fusidico. Se incluye una revisión de la farmacocinética, mecanismos de acción, efectos colaterales y sus usos clínicos en dermatologia veterinaria. Se presentan recomendaciones generales para la terapia antibacteriana tópica. [Guaguere, E. Topical treatment of canine and feline pyoderma. (Tratamiento topico de la pioderma canina y felina). Veterinary Dermatology 1996; 7: 145-151.] Zusammenfassung- Diese Veröffentlichung besteht in einer Übersicht von häufig verwendeten topischen antibakteriellen Arzneimitteln: Benzoylperoxid, Chlorhexidin, Povidon-Jod, Ethyllaktat, Triklosan, Mupirocin, Neomycin, Polymyxin B, Bacitracin und Fusidinsäure. Mit eingeschlossen ist eine Übersicht über Pharmakokinetik, Wirkungsweise, Nebenwirkungen und klinische Anwendung in der Veterinärdermatologie. Allgemeine Empfehlungen für die lokale antibakterielle Therapie werden dargestellt. [Guaguere, E. Topical treatment of canine and feline pyoderma (Lokale Behandlung von kaninen und felinen Pyodermien). Veterinary Dermatology 1996; 7: 145-151.].
Insights
This review covers common topical antibacterials for veterinary dermatology, including their pharmacokinetics, action, side effects, and uses. It provides general recommendations for effective topical antibacterial therapy in pets.
Area of Science:
- Veterinary Dermatology
- Pharmacology
- Microbiology
Background:
- Pyoderma is a common skin infection in dogs and cats.
- Topical antibacterial treatments are frequently used in veterinary dermatology.
- Understanding the properties of these agents is crucial for effective treatment.
Purpose of the Study:
- To review commonly used topical antibacterial medications in veterinary dermatology.
- To detail the pharmacokinetics, modes of action, adverse effects, and clinical uses of these agents.
- To provide general recommendations for topical antibacterial therapy.
Main Methods:
- Literature review of topical antibacterial medications.
- Analysis of pharmacokinetic data, mechanisms of action, and adverse effects.
- Compilation of clinical uses and therapeutic recommendations.
Main Results:
- Detailed review of benzoyl peroxide, chlorhexidine, povidone iodine, ethyl lactate, triclosan, mupirocin, neomycin, polymyxin B, bacitracin, and fusidic acid.
- Information on pharmacokinetics, modes of action, adverse effects, and clinical applications provided for each agent.
- General recommendations for topical antibacterial therapy are presented.
Conclusions:
- A comprehensive understanding of topical antibacterials is essential for treating canine and feline pyoderma.
- The review provides a valuable resource for veterinarians selecting and using these medications.
- Evidence-based recommendations support optimal therapeutic outcomes.
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