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Domperidone Withdrawal in a Nursing Female with Pre-existing Psychiatric Illness: A Case Report
Verinder Sharma1, Sapna Sharma2, Minakshi Doobay3
1Department of Psychiatry, Western University, Ontario, ON, Canada.
Background:
In this report, we describe a case of domperidone withdrawal in a woman with a history of major depressive disorder and obsessive-compulsive disorder (OCD), who experienced a recurrence of these disorders after stopping domperidone.
Case Presentation:
The symptoms improved after the restarting of domperidone and disappeared gradually as the drug was tapered and discontinued. Clinicians should consider domperidone withdrawal a differential diagnosis in women with a history of depression or anxiety who present with an acute onset of these symptoms following the abrupt discontinuation of domperidone.
Conclusion:
A gradual taper off of the drug may be effective in minimizing withdrawal symptoms and obviate the need for psychotropic drug use.
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