Rapidly progressive heart failure after dual-chamber pacemaker implantation
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Updated: Oct 17, 2025

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Claire Seydoux1, Philipp Suter2, Denis Graf3
1Department of Internal Medicine, HFR Fribourg Hopital cantonal, Fribourg, Switzerland.
Insights
Pacing-induced cardiomyopathy (PICM) can cause heart failure after pacemaker implantation. Upgrading to cardiac resynchronization therapy (CRT) can rapidly resolve symptoms and improve heart function.
Area of Science:
- Cardiology
- Electrophysiology
- Heart Failure Research
Background:
- Pacing-induced cardiomyopathy (PICM) is heart failure (HF) linked to high-burden right ventricular pacing.
- Symptoms can range from subclinical to severe, appearing weeks to years post-implantation.
- Risk factors for PICM necessitate careful patient selection for pacemaker (PM) or cardiac resynchronization therapy (CRT) implantation.
Observation:
- An 82-year-old patient developed acute congestive HF and reduced LVEF 30 days after dual-chamber PM implantation for high-grade AV block.
- The patient presented with symptoms of acute heart failure and a significantly decreased left ventricular ejection fraction (LVEF).
Findings:
- Treatment with HF medication and upgrade to CRT led to rapid symptom resolution.
- LVEF normalized within one month following the CRT upgrade.
Implications:
- This case highlights the potential for PICM following standard PM implantation.
- Early recognition and intervention with CRT can effectively manage and reverse PICM.
- Optimizing patient selection for initial pacing strategies may prevent PICM development.
Abstract:
Pacing-induced cardiomyopathy (PICM) consists of heart failure (HF) associated with a drop in the left ventricular ejection fraction (LVEF) in the setting of high-burden right ventricular pacing, with presentation that may range from subclinical to severe. Time to manifestation can go from weeks to years after device implantation. Treatment typically consists in an upgrade to a cardiac resynchronisation therapy (CRT) or His bundle pacing (HisP). Several risk factors for PICM have been described and should be considered before pacemaker (PM) implantation, as thorough patient selection for de novo CRT or HisP, may preclude its manifestation. We present the case of an 82-year-old patient presenting with acute congestive HF and new severely reduced LVEF, 30 days following dual chamber PM implantation for high-grade atrioventricular block. Treatment with HF medication and upgrade to a CRT permitted rapid resolution of the symptoms and normalisation of the LVEF at 1-month follow-up.
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