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Updated: Oct 17, 2025

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Superior Mesenteric Artery Syndrome Accompanied by Acute-onset Type 1 Diabetes Complicated with Graves' Disease
Mai Sue-Nagumo1, Shunichi Matsumoto1, Eijiro Yamada1
1Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Japan.
Abstract:
A 35-year-old man experienced general fatigue and could not eat solid food because of nausea and vomiting. His weight abruptly decreased from 49 to 45 kg after 2 weeks. A detailed examination indicated superior mesenteric artery syndrome (SMAS) accompanied by acute-onset type 1 diabetes complicated by Graves' disease, referred to as autoimmune polyglandular syndrome type 3A (APS3A). Although SMAS has a good prognosis, some cases require emergency surgery, especially when complicated by gastric perforation. In our case, APS3A and SMAS developed rapidly and at approximately the same time, resulting in a cycle of mutual exacerbation.
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