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Management dilemmas in pineoblastoma recurrence diagnosed during pregnancy
Sonal Garg1, Dilip K Maurya1, Gopalakrishnan M Sasidharan2
1Department of Obstetrics & Gynaecology, Jawaharlal Institute of Post-graduate Medical Education & Research (JIPMER), Puducherry, India.
Obstetric Medicine
|October 14, 2021
Summary
This case study details a rare pineoblastoma recurrence during pregnancy. It highlights the diagnostic and therapeutic challenges of managing this aggressive brain tumor in expectant mothers.
Area of Science:
- Neuro-oncology
- Maternal-fetal medicine
Background:
- Pineoblastoma is a rare, aggressive intracranial neoplasm with a high risk of craniospinal metastasis.
- Pregnancy presents unique challenges for managing rare brain tumors due to treatment contraindications and potential fetal risks.
Observation:
- A pregnant woman at five months gestation presented with a recurrence of pineoblastoma.
- The patient had previously defaulted adjuvant therapy after initial surgical decompression for the primary tumor.
Findings:
- The case underscores the rarity of pineoblastoma presenting during pregnancy, with only one prior report.
- Management involved addressing both the maternal tumor burden and the risks associated with pregnancy.
Implications:
- This case highlights the critical need for careful monitoring and tailored treatment strategies for rare intracranial neoplasms during pregnancy.
- Further research is needed to establish optimal management protocols for pineoblastoma in pregnant patients to improve maternal and fetal outcomes.

