Myricetin: A comprehensive review on its biological potentials

Area of Science:

• Nutritional Science
• Pharmacology
• Biochemistry

Background:

• Myricetin is a dietary flavonoid with established health-promoting properties.
• It is abundant in various plant-based foods like fruits, vegetables, tea, and wine.
• Rich botanical sources include families such as Myricaceae and Polygonaceae.

Purpose of the Study:

• To comprehensively review the therapeutic potential of myricetin.
• To elucidate the underlying mechanisms of action for its health benefits.
• To incorporate the latest research findings on myricetin's bioactivity.

Main Methods:

• Literature review of scientific studies on myricetin.
• Analysis of preclinical and clinical trial data.
• Exploration of myricetin's effects on cellular processes.

Main Results:

• Myricetin exhibits diverse therapeutic effects, including anticancer, antidiabetic, anti-inflammatory, and cardioprotective properties.
• Its health benefits are linked to modulation of key cellular pathways like apoptosis, glycolysis, and lipid metabolism.
• Clinical trials have investigated its efficacy in cancer and diabetes mellitus.

Conclusions:

• Myricetin is a promising natural compound with broad therapeutic applications.
• Understanding its mechanisms of action is crucial for developing myricetin-based health interventions.
• Further research is warranted to fully harness its potential for disease prevention and treatment.