Total penectomy in a hemodialysis-dependent patient: Calciphylaxis-induced penile gangrene

Penile gangrene secondary to calciphylaxis is rare. A case of gangrene of the penis in a chronic renal failure patient is reported. Extensive vascular calciphylaxis was observed within the penis. A 76-year old man with history of four year-course of hemodialysis complained of pain in the glans penis and subsequent swelling of the penile shaft. Coagulation necrosis of the glans and elevated serum inflammation markers suggested penile infection. As conservative therapies were ineffective, penectomy was performed to prevent systemic sepsis. In the cross sections of the amputated penis, the disease progression from wet gangrene to coagulation necrosis was clearly demonstrated.