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Updated: Sep 12, 2026

Murine Salivary Functional Assessment via Pilocarpine Stimulation Following Fractionated Radiation
Published on: May 4, 2018
Pulp innervation after radiation therapy
Abstract:
Decreased sensitivity was observed in teeth within and adjacent to an irradiated field. Mandibular teeth outside the field and distal to the irradiated mandibular nerve trunk showed an immediate decrease in sensitivity, Maxillary teeth outside the field showed a delayed decrease in sensitivity. Blood flow rates and nutrition were also related to time. Neurons are though to be relatively radio-resistant and few changes were seen histologically after radiation therapy. However, functional impairment was observed in histologically normal tissue.
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