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Updated: Oct 17, 2025
Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model
Published on: October 31, 2010
A simple algorithm for selecting cases to investigate acute and early HIV infections in low- and middle-income
Elaine Monteiro Matsuda1, Cintia Mayumi Ahagon2, Luana Portes Ozório Coelho2
1Infectious Diseases Outpatient Clinic, Santo André Health Secretary, Santo André, São Paulo, Brazil.
Abstract:
We documented the outcome of an over 10-year (2011-2021) effort to diagnose acute and early HIV infections (AEHI) in an Infectious Diseases Outpatient Clinic with limited resources. Of a total of 132, 119 HIV-RNA tests were performed from 2017 to 2020, 12 cases were identified, using a simple algorithm: risk exposure of 6 weeks or less before the visit and/or symptoms compatible with acute retroviral syndrome 7-30 days after exposure and/or undetermined 3rd generation rapid diagnostic test or serology. AEHI diagnoses varied from 2.4% among asymptomatic to 25% for undetermined serology cases using this simple screening applicable to different settings.
