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Published on: December 29, 2015
Complete Circular Genome Sequences of Three Bacillus cereus Group Strains Isolated from Positive Blood Cultures from
Mariem Ben Khedher1,2,3, Fredrik Nindo1,2,3, Alicia Chevalier1,4
1Bacteriology Laboratory, Archet 2 Hospital, CHU, University Côte d'Azur, Nice, France.
Insights
Researchers sequenced the genomes of three Bacillus cereus group strains from infant blood infections. This provides crucial data for understanding and combating these serious hospital-acquired infections in vulnerable populations.
Area of Science:
- Microbiology
- Genomics
- Infectious Diseases
Background:
- Bacillus cereus group strains can cause severe infections, particularly in vulnerable infant populations.
- Hospitalized premature and immunocompromised infants are at high risk for bloodstream infections.
Purpose of the Study:
- To report the complete genome sequences of three Bacillus cereus group strains.
- To provide genomic resources for studying infant infections caused by these bacteria.
Main Methods:
- Isolation of Bacillus cereus group strains from infant blood cultures.
- Whole-genome sequencing using Illumina HiSeq X Ten (short reads) and Oxford Nanopore MinION (long reads).
Main Results:
- Complete genome sequences of three Bacillus cereus group strains were obtained.
- The study provides high-quality genomic data for these clinically relevant isolates.
Conclusions:
- The generated genome sequences are valuable resources for future research.
- Understanding the genomics of Bacillus cereus group strains can aid in infection control and treatment strategies for infants.
Abstract:
We report here the complete genome sequences of three Bacillus cereus group strains isolated from blood cultures from premature and immunocompromised infants hospitalized in intensive care units in three French hospitals. These complete genome sequences were obtained from a combination of Illumina HiSeq X Ten short reads and Oxford Nanopore MinION long reads.

