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Related Concept Videos

Vaccinations01:51

Vaccinations

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Overview
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Cancer Vaccines01:30

Cancer Vaccines

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Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
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Cross-reactivity00:42

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Active versus Passive Immunity01:31

Active versus Passive Immunity

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Immunity, along with the ability to limit pathogen growth to prevent significant body tissue damage, can be gained either by (1) actively developing an immune response within the individual after exposure to a pathogen or after getting vaccinated or (2) passively transferring immune components from an immune individual to one who is nonimmune. Both these forms of immunity can be found naturally and in medical practices.
Active Immunity
Active immunity refers to the resistance one develops...
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Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

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Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
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Immunological Memory01:23

Immunological Memory

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Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
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Efficient Transfection of In vitro Transcribed mRNA in Cultured Cells Using Peptide-Poloxamine Nanoparticles
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[Vaccination against COVID-19].

Marek Štefan1, Pavel Dlouhý, Lenka Bezdíčková

  • 1Clinical microbiology and antibiotic center, Bulovka hospital, Prague,

Klinicka Mikrobiologie a Infekcni Lekarstvi
|October 14, 2021
PubMed
Summary

COVID-19 vaccination is crucial for managing the pandemic, offering significant protection against severe illness, hospitalization, and death. Vaccines remain highly effective against severe outcomes, even with new SARS-CoV-2 variants.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Immunology

Background:

  • The COVID-19 pandemic necessitates effective vaccination strategies.
  • Vaccination is proven to reduce severe illness, hospitalization, and mortality.
  • While protection against infection may vary with new variants, severe outcomes are still largely prevented.

Purpose of the Study:

  • To outline the importance and recommendations for COVID-19 vaccination.
  • To detail vaccine efficacy against severe disease and transmission.
  • To inform about vaccine recommendations for specific risk groups and age demographics.

Main Methods:

  • Review of current COVID-19 vaccine data and recommendations.
  • Analysis of vaccine effectiveness against SARS-CoV-2 and its variants.

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  • Identification of high-risk populations and vulnerable groups for vaccination.

    • Main Results:

    • Vaccination significantly reduces severe COVID-19, hospitalization, and death.
    • mRNA and vector vaccines are available, with ongoing recommendations for boosters.
    • High-risk groups (elderly, immunocompromised) and other demographics (children, pregnant women) are prioritized.

    Conclusions:

    • COVID-19 vaccination is essential for pandemic management and individual protection.
    • Booster doses are recommended for sustained immunity in selected populations.
    • Vaccination benefits outweigh the rare risks of serious side effects.