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Related Concept Videos

Learning Disabilities01:25

Learning Disabilities

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Learning disabilities are cognitive disorders caused by neurological impairments that affect cognitive functions like language and reading, without indicating overall intellectual or developmental challenges. These disabilities differ from global intellectual or developmental disabilities as they are limited to distinct cognitive functions. Common learning disabilities include dysgraphia, dyslexia, and dyscalculia, each of which impacts unique aspects of learning.
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Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round...
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Related Experiment Video

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Digital Handwriting Analysis of Characters in Chinese Patients with Mild Cognitive Impairment
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Progressive macrographia for block letter writing: A case study.

Carlo Semenza1, Serena De Pellegrin2, Silvia Facchini3

  • 1Department of Neuroscience & Padova Neuroscience Center, University of Padova, Padova, Italy.

Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
|October 14, 2021
PubMed
Summary
This summary is machine-generated.

This study details a rare progressive handwriting disorder, macrographia, affecting only block letters. Cognitive deficits and multifocal brain lesions may explain this unique presentation.

Keywords:
DysgraphiaMegalographiaNeglectProgressive macrographiaWorking memory

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Area of Science:

  • Neurology
  • Cognitive Neuroscience
  • Neuroimaging

Background:

  • Macrographia, characterized by abnormally large handwriting, is a rare symptom often associated with cerebellar diseases.
  • Previous cases typically show generalized effects across all writing styles.

Observation:

  • A unique case of progressive macrographia is presented, where letter size increases within words towards the lower-right.
  • This phenomenon was exclusively observed in block letter writing, sparing other allographic varieties.
  • Standard neuroimaging (MRI, PET) revealed no significant cerebellar or basal ganglia abnormalities.

Findings:

  • The progressive nature and allographic specificity of this macrographia are novel.
  • A combination of spatial attention, executive function, and working memory deficits is hypothesized.
  • Multifocal lesions in cortical areas and the corpus callosum correlate with the observed cognitive and writing impairments.

Implications:

  • This case expands the understanding of macrographia's diverse clinical presentations.
  • It highlights the complex interplay between specific cognitive functions, brain anatomy, and handwriting control.
  • Suggests potential for targeted cognitive rehabilitation strategies for patients with similar neurological conditions.