Related Experiment Video
Updated: Oct 16, 2025

07:10
Humanized NOD/SCID/IL2rγnull (hu-NSG) Mouse Model for HIV Replication and Latency Studies
Published on: January 7, 2019
15.9K
Routine HIV Testing and Outcomes: A Population-Based Cohort Study in Taiwan
Yi-Hsuan Chen1, Chi-Tai Fang2, Ming-Chieh Shih1
1Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan.
American Journal of Preventive Medicine
|October 15, 2021
Summary
Routine HIV testing significantly reduces late diagnosis and mortality for people diagnosed with HIV infection. Expanding this approach can improve public health and individual clinical outcomes.
Area of Science:
- Epidemiology
- Public Health
- Infectious Disease Management
Background:
- Early diagnosis and treatment are crucial for managing HIV/AIDS.
- Limited data exist on the benefits of routine HIV testing for patient outcomes.
Purpose of the Study:
- To compare outcomes of HIV diagnoses through routine versus non-routine testing.
- To assess the impact of routine HIV testing on late diagnosis, HIV-related mortality, and all-cause mortality.
Main Methods:
- Utilized Taiwan's national HIV/AIDS registry (1986-2014).
- Compared outcomes between routine (opt-out) and non-routine (risk-based) testing groups.
- Matched individuals by diagnosis year and adjusted for age, sex, transmission routes, and SES.
Main Results:
- Routine testing was linked to an 80% reduction in late HIV diagnosis.
- Associated with a 37% decrease in HIV-related mortality.
- Showed a 27% reduction in all-cause mortality.
Conclusions:
- Routine HIV testing leads to significantly better clinical outcomes.
- Expanding routine HIV testing in targeted settings can enhance HIV epidemic control and patient care.
Related Concept Videos
Retrovirus Life Cycles
47.6K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
47.6K
Longitudinal Research
12.7K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
12.7K
Bioavailability Study Design: Healthy Subjects Versus Patients
23
Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...
23

