Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide

Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide

Alkenes are converted to 1,2-diols or glycols through a process called dihydroxylation. It involves the addition of two hydroxyl groups across the double bond with two different stereochemical approaches, namely anti and syn. Dihydroxylation using osmium tetroxide progresses with syn stereochemistry.

Oxidative Cleavage of Alkenes: Ozonolysis

Oxidative Cleavage of Alkenes: Ozonolysis

In ozonolysis, ozone is used to cleave a carbon–carbon double bond to form aldehydes and ketones, or carboxylic acids, depending on the work-up.
Ozone is a symmetrical bent molecule stabilized by a resonance structure.

Oxidation of Alkenes: Syn Dihydroxylation with Potassium Permanganate

Oxidation of Alkenes: Syn Dihydroxylation with Potassium Permanganate

Alkenes can be dihydroxylated using potassium permanganate. The method encompasses the reaction of an alkene with a cold, dilute solution of potassium permanganate under basic conditions to form a cis-diol along with a brown precipitate of manganese dioxide.

Oxidation of Alkenes: Anti Dihydroxylation with Peroxy Acids

Oxidation of Alkenes: Anti Dihydroxylation with Peroxy Acids

Diols are compounds with two hydroxyl groups. In addition to syn dihydroxylation, diols can also be synthesized through the process of anti dihydroxylation. The process involves treating an alkene with a peroxycarboxylic acid to form an epoxide. Epoxides are highly strained three-membered rings with oxygen and two carbons occupying the corners of an equilateral triangle. This step is followed by ring-opening of the epoxide in the presence of an aqueous acid to give a trans diol.

Oxidation-Reduction Reactions

Oxidation-Reduction Reactions

Oxidation–Reduction Reactions

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Phase Engineering of Iridium Oxides Enables Direct Coupling of Proton Exchange Membrane Water Electrolysis With Intermittent Electrical Energy.

Advanced materials (Deerfield Beach, Fla.)·2026

Same author

Metabolic Engineering for Gibberellic Acid Production in <i>Fusarium fujikuroi</i>: Advances and Perspectives.

Molecules (Basel, Switzerland)·2026

Same author

CXCL10/SLC11A1 Axis Exacerbates Septic Liver Injury by Regulating Neutrophil Extracellular Traps Formation to Drive Macrophage Pro‑Inflammatory Polarization.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Same author

Organic-Inorganic Hybrid Hole-Selective Layer Interface Engineering for Enhanced Photoelectrochemical Water Oxidation on Bismuth Vanadate Photoanodes.

Advanced materials (Deerfield Beach, Fla.)·2026

Same author

Highly Interdiffused W-Ir Interfaces Enhances Acidic Oxygen Evolution.

Small (Weinheim an der Bergstrasse, Germany)·2026

Same author

Federated learning and digital twins for lifecycle optimization in Urban building renewal.

Scientific reports·2026

Search research articles

Related Experiment Video

Updated: Oct 16, 2025

Photochemical Oxidative Growth of Iridium Oxide Nanoparticles on CdSe@CdS Nanorods

Photochemical Oxidative Growth of Iridium Oxide Nanoparticles on CdSe@CdS Nanorods

Published on: February 11, 2016

Iridium metallene oxide for acidic oxygen evolution catalysis.

Qian Dang^1,2,3, Haiping Lin², Zhenglong Fan²

¹College of Chemistry, Chemical Engineering and Materials Science, Soochow University, 215123, Jiangsu, P. R. China.

Nature Communications

|October 15, 2021

Summary

Researchers developed a novel iridium metallene oxide, 1T-iridium dioxide (IrO2), using mechanochemistry and thermal treatment. This new material shows exceptional activity and stability for the oxygen evolution reaction, advancing catalytic applications.

More Related Videos

Synthesis of Platinum-nickel Nanowires and Optimization for Oxygen Reduction Performance

Synthesis of Platinum-nickel Nanowires and Optimization for Oxygen Reduction Performance

Published on: April 27, 2018

Heterogeneous Removal of Water-Soluble Ruthenium Olefin Metathesis Catalyst from Aqueous Media Via Host-Guest Interaction

Heterogeneous Removal of Water-Soluble Ruthenium Olefin Metathesis Catalyst from Aqueous Media Via Host-Guest Interaction

Published on: August 23, 2018

Related Experiment Videos

Last Updated: Oct 16, 2025

Photochemical Oxidative Growth of Iridium Oxide Nanoparticles on CdSe@CdS Nanorods

Photochemical Oxidative Growth of Iridium Oxide Nanoparticles on CdSe@CdS Nanorods

Published on: February 11, 2016

Synthesis of Platinum-nickel Nanowires and Optimization for Oxygen Reduction Performance

Synthesis of Platinum-nickel Nanowires and Optimization for Oxygen Reduction Performance

Published on: April 27, 2018

Heterogeneous Removal of Water-Soluble Ruthenium Olefin Metathesis Catalyst from Aqueous Media Via Host-Guest Interaction

Heterogeneous Removal of Water-Soluble Ruthenium Olefin Metathesis Catalyst from Aqueous Media Via Host-Guest Interaction

Published on: August 23, 2018

Area of Science:

Materials Science
Catalysis
Electrochemistry

Background:

Developing advanced materials is crucial for efficient catalytic applications.
Optimizing materials for high atomic utilization, activity, and stability is a key challenge.

Purpose of the Study:

To synthesize and characterize a novel iridium metallene oxide, 1T-iridium dioxide (IrO2).
To evaluate the catalytic performance of 1T-IrO2 for the oxygen evolution reaction (OER).

Main Methods:

Synthesis via a combination of mechanochemistry and thermal treatment in an alkaline medium.
Electrochemical characterization including overpotential, turnover frequencies, and chronopotentiometry.
Theoretical calculations to understand the reaction mechanism.

Main Results:

1T-IrO2 exhibits high activity for OER with a low overpotential (197 mV at 10 mA cmgeo-2).
Achieved high turnover frequencies (4.2 s-1 UPD, 3.0 s-1 BET) at 1.50 V vs. RHE.
Demonstrated excellent stability with minimal degradation after 126 hours of testing at high current density (250 mA cmgeo-2).

Conclusions:

The 1T-IrO2 material offers a promising platform for advanced catalytic applications.
Theoretical calculations indicate optimal *OH formation free energy at the Ir active site, explaining the enhanced performance.
This discovery opens new avenues for designing metallene oxides in catalysis.