How to reduce uncommon but severe transcatheter aortic valve implantation complications: stroke, thrombosis,

Francesco Saia1, Mateusz Orzalkiewicz1

  • 1Cardiac Unit, Cardio-Thoracic-Vascular Department, IRCCS University Hospital of Bologna, Policlinico S. Orsola (Pav. 23), Via Massarenti, 9, 40138 Bologna, Italy.

Insights

Transcatheter aortic valve implantation (TAVI) is a safe alternative for severe aortic stenosis. This review details uncommon TAVI complications like stroke and endocarditis, focusing on prevention.

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology

Background:

  • Transcatheter aortic valve implantation (TAVI) is a primary treatment for severe symptomatic aortic stenosis.
  • TAVI offers a less invasive alternative to surgical aortic valve replacement, suitable for all surgical risk levels.
  • Improvements in technology and operator experience have reduced TAVI's periprocedural complication rates.

Purpose of the Study:

  • To review uncommon but severe complications following TAVI.
  • To discuss the incidence, risk factors, and prevention strategies for these delayed complications.

Main Methods:

  • Literature review focusing on post-TAVI complications.
  • Analysis of incidence, predictive factors, and preventive measures for stroke, infective endocarditis, valve thrombosis, and cognitive decline.

Main Results:

  • While periprocedural complications have decreased, uncommon events like stroke, endocarditis, valve thrombosis, and cognitive decline can occur post-TAVI.
  • These complications may manifest during follow-up but can also arise periprocedurally.
  • Identification of predictive factors and preventive strategies is crucial for patient management.

Conclusions:

  • TAVI is a well-established procedure with declining complication rates.
  • Awareness and proactive management of uncommon delayed complications are essential for optimizing long-term TAVI outcomes.
  • Further research into predictive factors and preventive strategies for these rare events is warranted.

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