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A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
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Neonatal Sepsis Due to Bacillus subtilis
Panagiotis K Lampropoulos1, Despoina Gkentzi2, Sotiris Tzifas1
1Pediatrics, University Hospital Patras, Patras, GRC.
Cureus
|October 15, 2021
Summary
Bacillus subtilis, a common environmental bacterium, rarely causes late-onset neonatal sepsis. This case highlights a rare instance of B. subtilis infection in a newborn, emphasizing its potential as a pathogen.
Area of Science:
- Microbiology
- Neonatal Medicine
- Infectious Diseases
Background:
- Bacillus subtilis is a Gram-positive bacterium typically found in soil and the human gut.
- It is generally considered to have low virulence and rarely causes disease in humans.
Observation:
- A rare case of late-onset neonatal sepsis is presented.
- The newborn exhibited multiple positive blood cultures.
Findings:
- Bacillus subtilis was isolated as the causative pathogen from the blood cultures.
- This indicates B. subtilis can act as a significant pathogen in vulnerable neonatal populations.
Implications:
- This case expands the understanding of potential pathogens causing neonatal sepsis.
- Clinicians should consider B. subtilis in the differential diagnosis of neonatal infections, especially with unusual presentations.

