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Fabrication of Tongue Extracellular Matrix and Reconstitution of Tongue Squamous Cell Carcinoma In Vitro
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Tongue Cancer in a Young Male
Gyanendra Bagale1, Sandip R Pradhan2, Archana Basnet3
1Otorhinolaryngology, Patan Academy of Health Sciences, Kathmandu, NPL.
Cureus
|October 15, 2021
Summary
This case study highlights a rare instance of oral squamous cell carcinoma in a 29-year-old male, emphasizing the importance of considering early-onset cancers. Early detection and treatment, including surgery and radiotherapy, are crucial for managing this aggressive oral cancer.
Area of Science:
- Oncology
- Oral Medicine
Background:
- Oral squamous cell carcinoma (OSCC) typically affects individuals over 60.
- Early-onset OSCC in patients under 30 is exceptionally rare.
Observation:
- A 29-year-old male presented with an ulceroproliferative growth on the left lateral tongue.
- The patient reported a history of tobacco- and betel nut chewing since age 14.
Findings:
- Histopathological examination confirmed squamous cell carcinoma.
- Staging revealed cT4a N0 M0, indicating an advanced local tumor stage without nodal or distant metastasis.
Implications:
- This case underscores the need to consider OSCC in younger populations, particularly those with significant risk factors.
- Aggressive management involving surgery and adjuvant radiotherapy is essential for advanced-stage disease in young adults.
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