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Updated: Oct 16, 2025

Author Spotlight: Advancing Corneal Innervation Research Through Innovative Models
Published on: December 8, 2023
Corneal Neurotization via Dual Nerve Autografting
Emily Sarah Charlson1, John Paul Pepper2, Andrea Lora Kossler3
1Oculofacial, Orbital and Aesthetic Plastic Surgery, Department of Ophthalmology, Pacific Eye Associates, California Pacific Medical Center, San Francisco, California.
Abstract:
Corneal neurotization is a fast-evolving surgical procedure for sensory reinnervation in neurotrophic keratopathy. After neurotization, prior reports document return of corneal sensation on average 8 months after surgery with 38 mm of sensation gain measured via cochet bonnet esthesiometer testing. Here, the authors describe a dual nerve grafting approach via simultaneous parallel sural nerve grafts from both the supratrochelar and supraorbital nerves to the affected contralateral cornea with return of sensation by postoperative week 11.

