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Related Experiment Video

Updated: Oct 16, 2025

Intraoperative Ultrasound in Spinal Surgery
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Neuronavigated Ultrasound in Neuro-Oncology: A True Real-Time Intraoperative Image.

Cristian de Quintana-Schmidt1, Laura Salgado-Lopez2, Juan Angel Aibar-Duran1

  • 1Department of Neurosurgery, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

World Neurosurgery
|October 16, 2021
PubMed
Summary

Neuronavigated ultrasound provides excellent visualization of brain tumors during surgery without significantly increasing operative time. This real-time imaging method aids in precise tumor resection and residual tumor detection.

Keywords:
Brain tumorExtent of resectionIntraoperative imageNeuronavigated ultrasoundSurgical time

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Area of Science:

  • Neurosurgery
  • Medical Imaging
  • Oncology

Background:

  • Intraoperative ultrasound is a rapid imaging technique in neuro-oncology.
  • Previous studies have not quantified the additional surgical time required for intraoperative ultrasound.

Purpose of the Study:

  • To evaluate the utility of navigated intraoperative ultrasound in brain tumor resection.
  • To assess lesion visibility, concordance with MRI, and surgical time.
  • To determine the effectiveness in residual tumor detection.

Main Methods:

  • Prospective study of 100 patients undergoing intra-axial brain tumor resection.
  • Utilized navigated intraoperative ultrasound.
  • Assessed lesion visibility, MRI concordance, ultrasound usage time, and tumor resection percentage.

Main Results:

  • 96% of lesions were visualized; 71% had clearly delimited borders.
  • Concordance with preoperative MRI was 78%.
  • Mean ultrasound probe covering time was 2.16 min; mean acquisition time was 2.49 min.
  • Ultrasound demonstrated 94.4% sensitivity and 100% specificity for residual tumor detection.

Conclusions:

  • Neuronavigated ultrasound is a real-time intraoperative imaging method.
  • It does not significantly increase surgical time.
  • It offers optimal visualization of intra-axial brain lesions and residual tumors.