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[Development of a tool to help optimizing drug prescriptions in pediatric units in Côte d'Ivoire: GOPP tool]

E Doffou1, B A Kamenan1, D P Abrogoua2

  • 1Laboratoire de pharmacie clinique et thérapeutique, UFR sciences pharmaceutiques et biologiques, université Felix Houphouët-Boigny, Abidjan, Cote d'Ivoire; Service de pharmacie, centre hospitalier et universitaire de Cocody, Abidjan, Cote d'Ivoire.

Annales Pharmaceutiques Francaises
|October 17, 2021
PubMed

Insights

This study developed a tool to optimize drug management in pediatric units in Côte d

Area of Science:

  • Pharmacology and Therapeutics
  • Pediatric Drug Management
  • Health Informatics

Background:

  • Suboptimal drug management in pediatric units poses significant risks.
  • A need exists for evidence-based tools to guide pediatric prescribing in Côte d'Ivoire.
  • Current prescription practices require optimization to improve patient outcomes.

Purpose of the Study:

  • To develop a novel tool for optimizing drug management in pediatric care.
  • To enhance clinical and therapeutic decision-making in pediatric units.
  • To address inappropriate prescribing in pediatric populations in Côte d'Ivoire.

Main Methods:

  • Prescription review of 4992 lines for 881 pediatric patients (1 month-15 years).
  • Development of a list of 54 potential Inappropriate Prescribings (IPs).
  • Validation of IPs using a two-round Delphi method with 23 pediatric experts.
  • Selection criteria: >70% agreement (round 1) and >80% agreement (round 2) for IPs.

Main Results:

  • A final list of 52 validated IPs was established.
  • The tool development incorporated rationales and therapeutic recommendations for each IP.
  • Key conditions addressed include malaria (15%), rhinitis (12%), and bacterial infections (8%).

Conclusions:

  • The developed tool, GOPP (Gestion Optimisée des Prescriptions en Pédiatrie), aims to improve pediatric drug management.
  • Implementation of the GOPP tool is expected to enhance patient care in Côte d'Ivoire's pediatric units.
  • This tool supports evidence-based prescribing and optimizes therapeutic strategies.
Abstract

Keywords:
Côte d’IvoireGOPP toolInappropriate prescribingOutil GOPPPediatricsPrescription médicamenteuse inappropriéePédiatrie

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