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Kidney length normative values in children aged 0-19 years - a multicenter study.
Łukasz Obrycki1, Jędrzej Sarnecki2, Marianna Lichosik3
1Department of Nephrology, Kidney Transplantation and Hypertension, Children's Memorial Health Institute, al. Dzieci Polskich 20, 04-730, Warsaw, Poland. l.obrycki@ipczd.pl.
This study establishes new ultrasound-based kidney length norms for children aged 0-19 years, utilizing height as the primary predictor. These findings provide crucial pediatric kidney reference values for clinical use.
Area of Science:
- Pediatric Nephrology
- Radiology
- Biostatistics
Background:
- Current pediatric kidney length norms lack comprehensive data, often from small studies and without kidney function assessment.
- Existing norms primarily focus on newborns and infants, leaving a gap for older children.
Purpose of the Study:
- To develop ultrasound-based kidney length normative values for European Caucasian children aged 0-19 years.
- To establish height-related kidney length curves and tables using robust statistical methods.
Main Methods:
- Sonographic kidney length assessment in 1,758 children (aged 0-19 years) with normal kidney function.
- Correlation analysis with anthropometric parameters (age, height, BSA, BMI) and estimated glomerular filtration rate.
- Application of the LMS method for generating height-related percentile curves and tables.
Main Results:
- Kidney length showed significant correlation with height, age, body surface area, and BMI.
- Height was identified as the strongest predictor of kidney length (adjusted R²=0.87).
- No clinically significant differences in kidney length were observed between sexes or body positions.
Conclusions:
- Novel height-related LMS-percentile curves and tables for pediatric kidney length are presented.
- These normative values are applicable for children from birth to 19 years.
- Statural height is the most significant predictor for estimating kidney length in children.
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