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Asymmetric Walkway: A Novel Behavioral Assay for Studying Asymmetric Locomotion
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Gait asymmetry is associated with performance-based physical function among adults with lower-limb amputation
Mayank Seth1, Peter C Coyle2, Ryan T Pohlig3
1Delaware Limb Loss Studies, Department of Physical Therapy, University of Delaware, Newark DE, USA.
Physiotherapy Theory and Practice
|October 18, 2021
Summary
Gait asymmetry in lower-limb amputations is linked to poorer physical function. Addressing step length and stance time differences can improve mobility outcomes for amputees.
Area of Science:
- Biomechanics
- Rehabilitation Medicine
- Orthopedics
Background:
- Adults with lower-limb amputation often experience asymmetrical gait.
- This gait asymmetry is associated with diminished functional outcomes and reduced quality of life.
Purpose of the Study:
- To investigate the relationship between gait asymmetry and performance-based physical function in adults with lower-limb amputation.
Main Methods:
- A cross-sectional study analyzed 38 adults with unilateral transtibial or transfemoral amputations.
- Gait analysis captured step length and stance time asymmetry at self-selected and fast walking speeds.
- Participants completed the Timed Up and Go (TUG), 10-Meter Walk Test (10mwt), and 6-Minute Walk Test (6MWT).
Main Results:
- Significant correlations were found between gait asymmetry (step length, stance time) and all performance-based measures (p < .001 to p = .035).
- Gait measures at fast walking speeds explained a higher percentage of variance in TUG-time (70.0%), 10mwt-speed (59.8%), and 6MWT-distance (51.8%) compared to self-selected speeds.
- Models using gait measures at self-selected speeds explained 40.1%-46.8% of the variance in functional outcomes.
Conclusions:
- Increased step length and stance time asymmetry are associated with poorer performance on the TUG, 10mwt, and 6MWT.
- Gait asymmetry appears to be a significant factor contributing to reduced functional capacity in individuals with lower-limb amputations.

