[A patient with recurrent multiloculated hydrocephalus after Cryptococcal ventriculitis].

Area of Science:

• Neurology
• Infectious Diseases
• Neurosurgery

Background:

• Cryptococcal meningitis can lead to serious neurological complications.
• Adult-onset hydrocephalus is uncommon, and multiloculated hydrocephalus (MLH) is a rare subtype.

Observation:

• A 63-year-old male developed disorientation and amnesia after Cryptococcal ventriculitis.
• Brain MRI revealed dilation of the left lateral ventricle's inferior horn, indicative of noncommunicating hydrocephalus.
• Further symptoms of urinary dysfunction and gait disturbance emerged, associated with bilateral anterior horn dilation.

Findings:

• Two ventriculoperitoneal shunts (VPS) were surgically placed to address the noncommunicating hydrocephalus.
• Post-VPS interventions led to significant improvement in the patient's cognitive and motor functions.

Implications:

• This case underscores the importance of recognizing and managing rare neurological sequelae of fungal meningitis.
• Timely surgical intervention, such as VPS, can effectively alleviate symptoms and improve quality of life in patients with complex hydrocephalus.
• Further research into the pathogenesis and long-term management of MLH post-meningitis is warranted.