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Pediatric Extramedullary Epidural Spinal Teratomas: A Case Report and Review of the Literature
David G Deckey1, Andrea Fernandez2, Nina J Lara3
1Mayo Clinic Arizona, Department of Orthopaedic Surgery, Phoenix, AZ, USA.
Insights
Pediatric spinal teratomas are rare, presenting diagnostic challenges in infants. Surgical resection is key for treatment, with MRI aiding diagnosis and follow-up.
Area of Science:
- Pediatric Neurosurgery
- Central Nervous System Oncology
Background:
- Teratomas are rare pediatric central nervous system (CNS) neoplasms, with intraspinal locations being exceptionally uncommon.
- Clinical presentation of intraspinal teratomas in infants is often ambiguous due to limited verbal and motor development.
Observation:
- A 7-month-old male presented with thoracic scoliosis and a congenital spinal prominence.
- MRI revealed an extensive epidural mass compressing the thoracic spinal cord, causing severe stenosis.
Findings:
- Complete surgical resection of the mature teratoma was achieved via posterior decompression and laminectomy.
- Histopathological analysis confirmed the diagnosis of a mature teratoma.
Implications:
- Extramedullary epidural teratomas require prompt surgical intervention, especially with cord compression.
- MRI is valuable for diagnosis and postoperative surveillance, but histopathology is definitive.
- Close monitoring for spinal deformity and recurrence is essential post-surgery.
Background:
Teratomas in the pediatric population are most commonly found in the sacrococcygeal region. Pediatric intraspinal teratomas, however, are an exceedingly rare central nervous system (CNS) neoplasm. The clinical presentation of these intraspinal neoplasms can vary significantly and thus can be difficult to identify in infants less than one year of age where verbal expression and motor development are still lacking. Case Description. A 7-month-old, previously healthy male presented with a thoracic scoliosis and an asymptomatic right midupper thoracic spinal prominence present since birth. MRI revealed an extensive heterogenous mass in the right epidural space from T5-T6 and the right paravertebral space, resulting in severe spinal stenosis. Outcome. Complete resection of the tumor, including a three-level neurotomy, was achieved by posterior decompression/laminectomy. The final tumor was consistent with a mature teratoma. The surgical resection was performed without any immediate complications.
Conclusions:
Extramedullary epidural teratomas are exceptionally rare tumors in the pediatric population. Clinical presentation can be ambiguous, particularly in an infant. MRI was useful in suggesting a teratoma as a potential diagnosis and for postoperative surveillance for recurrence. However, histopathological analysis remains the gold standard for definitive diagnosis. Surgical resection is the mainstay of treatment, especially in the setting of cord compression and progressive loss of motor function. Close follow-up is crucial to monitor for progressive spinal deformity or recurrence.
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