Lymph Node Involvement in Oesophageal Carcinoma: A Single-Centre Observational Study From Western India
Ajay K Boralkar1, Abdul Rafe1, Bhushan Bhalgat1
1Department of Surgery, Government Cancer Hospital, Aurangabad, IND.
Cureus
|October 18, 2021
Summary
Lymph node involvement is crucial in esophageal cancer prognosis. This study found 50% of squamous cell carcinoma cases had lymph node metastasis, with thoracic nodes most frequently affected.
Area of Science:
- Oncology
- Gastroenterology
- Surgical Pathology
Background:
- Lymph node metastasis is a key prognostic factor in esophageal cancer.
- Understanding lymphadenopathy patterns is vital for treatment strategies.
Purpose of the Study:
- To describe lymph node involvement in esophageal carcinoma patients.
- To analyze patterns of lymphadenopathy in a tertiary care center in India.
Main Methods:
- A descriptive study of 31 esophageal carcinoma patients undergoing surgery.
- Inclusion of three-field or two-field lymph node dissections.
- Histopathological assessment of resected tumors and lymph nodes for metastasis.
Main Results:
- 17 out of 31 patients (54.8%) showed lymph node involvement.
- Squamous cell carcinoma (28 cases) had 50% lymph node involvement; adenocarcinoma (3 cases) had 100% involvement.
- Thoracic lymph nodes were most commonly involved (11 SCC, 2 adenocarcinoma cases).
Conclusions:
- Squamous cell carcinoma is the predominant esophageal cancer type in this region.
- Lymph node metastasis is common, particularly in thoracic regions.
- Advanced tumor stages (T2, T3) and poorly differentiated cancers show higher lymph node involvement rates.
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