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A Late Presentation of COVID-19 Vaccine-Induced Myocarditis

Nitesh Gautam1, Prachi Saluja1, Marat Fudim2

  • 1Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, USA.

Cureus
|October 18, 2021
PubMed

Insights

This case report details an elderly man who developed subacute myocarditis three months after his second COVID-19 mRNA vaccine dose. Fortunately, he experienced a rapid recovery, highlighting a favorable outcome for this rare vaccine side effect.

Area of Science:

  • Cardiology
  • Vaccinology
  • Public Health

Background:

  • The widespread adoption of COVID-19 mRNA vaccines has drastically reduced severe infections.
  • While generally safe and effective, rare cases of acute myocarditis have been reported post-vaccination, typically within days of the second dose.

Observation:

  • An elderly male presented with chest pain three months after his second COVID-19 mRNA vaccine dose.
  • Cardiac magnetic resonance imaging confirmed acute myocarditis.
  • No other risk factors for myocarditis were identified, leading to vaccine association.

Findings:

  • This case suggests a possible subacute presentation of myocarditis following COVID-19 vaccination, occurring months after the second dose.
  • The patient experienced a swift resolution of symptoms and was discharged within 72 hours.
  • Literature review and case summary of COVID-19 vaccine-associated myocarditis are included.

Implications:

  • This report expands the understanding of the temporal relationship between COVID-19 vaccination and myocarditis.
  • It highlights a potentially favorable prognosis for vaccine-associated myocarditis, even with a delayed presentation.
  • Further research into the mechanisms and long-term outcomes of vaccine-induced myocarditis is warranted.
Keywords:
atypical chest paincovid 19covid-19 vaccine complicationpost vaccination myocarditisvaccine

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