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Updated: Oct 16, 2025
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Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication
Published on: December 11, 2013
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Depression among predictors of intermittent claudication: A cross-sectional study
Gergely Tóth-Vajna1, Zsombor Tóth-Vajna2, Barna Konkoly Thege3,4
11 Institute of Behavioral Sciences, Semmelweis University, Budapest, Hungary.
Physiology International
|October 18, 2021
Summary
Depression significantly predicts intermittent claudication (IC) even after accounting for traditional risk factors. Managing mental health is crucial for patients with IC, alongside lifestyle changes.
Area of Science:
- Cardiovascular Health
- Mental Health Research
- Epidemiology
Background:
- Intermittent claudication (IC) is a common manifestation of peripheral artery disease.
- Depression is increasingly recognized as a comorbidity in chronic conditions.
- The independent association between depression and IC requires further investigation.
Purpose of the Study:
- To examine the relationship between depression and intermittent claudication (IC).
- To determine if depression predicts IC independently of traditional cardiovascular risk factors.
Main Methods:
- Cross-sectional study of 300 individuals.
- Assessed IC using the Edinburgh Claudication Questionnaire.
- Measured depression using a shortened Beck Depression Inventory.
- Controlled for age, sex, hypertension, diabetes, smoking, hypercholesterolemia, hazardous drinking, and BMI using binary logistic regression.
Main Results:
- Depression prevalence was 57.9% in the IC subgroup versus 16.1% in controls.
- Depressive symptomatology significantly predicted IC (OR: 1.08).
- Smoking, hazardous drinking, and hypercholesterolemia were also significant predictors of IC.
Conclusions:
- Depression is an independent predictor of intermittent claudication.
- A multidisciplinary approach is essential for managing patients with IC.
- Integrating mental health support and behavioral change strategies is vital for patient care.
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