A targeted extraction with solvent-free pressurized method based on analyte-like oxonium salts: An example for...

By using novel oxonium salts in "Sandwich" mode, an improved approach of targeted enrichment through a pressurized solvent-free extraction coupled with ultra-performance liquid chromatography/ultraviolet detection (UPLC-UV) analysis was developed for main bioactive flavonoids in bamboo leaves. As solid extractants, these salts have the same structural nucleus with analytes. By comparison, the yield of this new method was higher than that of reported ways, and the highest enrichment factor reached 394.22. The whole process was more consistent with pseudo-second order model (R²=0.9994) with the rate constant of 0.0537 (g/mg·min). Moreover, ideal selectivity, linearity, repeatability, limit of detection, limit of quantification, and recovery were all achieved.