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Circadian clocks guide dendritic cells into skin lymphatics

Stephan J Holtkamp1, Louise M Ince2, Coline Barnoud2

  • 1Biomedical Center (BMC), Institute for Cardiovascular Physiology and Pathophysiology, Walter Brendel Center for Experimental Medicine (WBex), Faculty of Medicine, Ludwig-Maximilians-Universität Munich, Planegg-Martinsried, Germany.

Nature Immunology
|October 19, 2021
PubMed
Summary

Immune cells called dendritic cells (DCs) migrate into lymphatic vessels in a daily rhythm, controlled by internal body clocks. This discovery impacts understanding of immune responses, vaccination, and therapies.

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