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Long-term follow-up of passive containment surgery in patients with aortic regurgitation

Fredrik Bredin1, Anders Franco-Cereceda1

  • 1Section of Cardiothoracic Surgery, Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.

Interactive Cardiovascular and Thoracic Surgery
|October 19, 2021
PubMed

Insights

Aortic regurgitation (AR) patients with left ventricular dilatation showed similar long-term cardiac improvements after aortic valve replacement, with or without the Acorn CorCap device.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Biomedical Engineering

Background:

  • Aortic regurgitation (AR) with left ventricular dilatation poses significant risks.
  • Aortic valve replacement (AVR) is a standard treatment.
  • The Acorn CorCap cardiac support device is used to enhance left ventricular function.

Purpose of the Study:

  • To evaluate the long-term effects of AVR with and without the Acorn CorCap device on cardiac dimensions, function, and coronary circulation in AR patients.
  • To compare the efficacy of AVR alone versus AVR plus the cardiac support device.

Main Methods:

  • A case-control study involving 10 patients with AR and left ventricular dilatation.
  • 5 patients underwent mechanical AVR and Acorn CorCap implantation; 5 underwent mechanical AVR alone.
  • Echocardiography assessed cardiac dimensions and function preoperatively and at 1, 5, and 10 years postoperatively.
  • Coronary circulation was evaluated using computed tomography angiography.

Main Results:

  • Aortic valve replacement led to rapid and sustained decreases in cardiac dimensions in both groups.
  • Cardiac function improved and remained stable at 10 years in both groups.
  • The Acorn CorCap device did not provide additional benefits in terms of reverse remodeling or cardiac function compared to AVR alone.
  • No coronary artery disease was observed in any patient.

Conclusions:

  • The Acorn CorCap cardiac support device does not offer additional long-term benefits for reverse remodeling or cardiac function in patients with AR and left ventricular dilatation undergoing AVR.
  • Aortic valve replacement alone effectively improves cardiac dimensions and function in these patients over the long term.

Keywords:
Aortic regurgitationAortic valve replacementPassive containment surgeryVentricular remodelling

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