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Methicillin-Resistant Staphylococcus aureus from Municipal Abattoirs in Nigeria: Showing Highly Similar Clones and

Ismail A Odetokun1, Sven Maurischat2, Victoria O Adetunji3

  • 1Department of Veterinary Public Health and Preventive Medicine, University of Ilorin, Ilorin, Nigeria.

Foodborne Pathogens and Disease
|October 19, 2021
PubMed

Insights

Methicillin-resistant Staphylococcus aureus (MRSA) strains were identified in Nigerian abattoirs from humans, animals, and the environment. Similar MRSA strains were found across these sources, highlighting the need for control measures to prevent transmission.

Area of Science:

  • Veterinary Medicine
  • Microbiology
  • Food Safety
  • Public Health

Background:

  • Methicillin-resistant Staphylococcus aureus (MRSA) poses a zoonotic risk, with limited data on Nigerian abattoir isolates.
  • Understanding MRSA epidemiology in food chain environments is crucial for public health.

Purpose of the Study:

  • To characterize genotypic and virulence factors of MRSA from Nigerian abattoirs.
  • To investigate the epidemiology and transmission dynamics of MRSA in this setting.

Main Methods:

  • MRSA isolates (n=18) from humans, slaughter animals, and environment underwent SCCmec typing, antimicrobial susceptibility testing (phenotypic and genotypic).
  • Multilocus sequence typing and DNA microarray analysis were performed on select strains, including a new spa type (t16571).

Main Results:

  • Two SCCmec types (IVa, V) and four clonal clusters (CC1, CC7, CC88, CC152) were identified.
  • A high prevalence of the Panton-Valentine Leukocidin gene (33.3%) was observed.
  • Similar MRSA strains were detected in humans, animals, and the abattoir environment.

Conclusions:

  • The presence of genetically similar MRSA strains across different sources in Nigerian abattoirs indicates a potential transmission cycle.
  • Implementing stringent hygiene and control measures in abattoirs is essential to mitigate MRSA spread to humans and food products.
Keywords:
MRSANigeriaabattoirsfood chaintransmissionvirulence

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