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The "heart brain" and neuromodulation for vasovagal syncope
Tolga Aksu1, Andre Davila2, Dhiraj Gupta3
1Yeditepe University Hospital, Department of Cardiology, Istanbul, Turkey.
The autonomic nervous system (ANS) plays a key role in vasovagal syncope (VVS). Catheter-based neuromodulation (CNA) of the cardiac ANS is now a common procedure, offering a new treatment approach.
Area of Science:
- Cardiology
- Neuroscience
- Anatomy
Background:
- The autonomic nervous system (ANS) is implicated in the development of vasovagal syncope (VVS).
- Catheter-based neuromodulation (CNA) targeting the intrinsic cardiac ANS has transitioned from experimental to clinical practice.
- This procedure is increasingly performed in major medical centers globally.
Purpose of the Study:
- To consolidate anatomical knowledge of the intrinsic cardiac ANS.
- To review clinical data on intrinsic cardiac neuromodulation.
- To offer practical guidance for electrophysiologists.
Main Methods:
- Review of anatomical terminologies related to the intrinsic cardiac ANS.
- Analysis of existing clinical data on cardiac neuromodulation procedures.
- Synthesis of anatomical and clinical information.
Main Results:
- The intrinsic cardiac ANS comprises specific anatomical structures crucial for its function.
- Clinical data demonstrate the evolving efficacy and safety of CNA for VVS.
- The review provides a unified perspective on the anatomy and clinical applications of CNA.
Conclusions:
- Understanding the intrinsic cardiac ANS anatomy is vital for effective neuromodulation.
- CNA represents a significant advancement in managing VVS.
- This review serves as a practical resource for electrophysiology professionals.
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