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Isolation of Myofibroblasts from Mouse and Human Esophagus
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[Primary giant laryngitis myofibroblastoma in a child: a case report]

Y Q Liu1, Q Li1, H Y Wu1

  • 1Department of Otorhinolaryngology Head and Neck Surgery, Children's Hospital of Nanjing Medical University,Nanjing 210008, China.

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Chinese Journal of Otorhinolaryngology Head and Neck Surgery
|October 20, 2021
PubMed
Abstract

No abstract available in PubMed .

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Rudolph Virchow discovered spindle-shaped cells called fibroblasts in 1858. Inactive fibroblasts, called fibrocytes, become activated by various stimuli, such as growth factors and inflammatory cytokines. Activated fibroblasts play a crucial role in wound healing, inflammation, formation of new blood vessels, and cancer progression. Uncontrolled activation of fibroblasts results in fibrosis, the excess deposition of fibrous tissue, which can lead to scarring and affect normal organs. This...

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