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BILATERAL AMYLOIDOSIS OF THREE EYELIDS. A CASE REPORT.

J Krásný, J Šach, H Hůlková

    Ceska a Slovenska Oftalmologie : Casopis Ceske Oftalmologicke Spolecnosti a Slovenske Oftalmologicke Spolecnosti
    |October 20, 2021
    PubMed
    Summary
    This summary is machine-generated.

    This case report details a rare instance of bilateral eyelid amyloidosis (AL type) in a man, successfully treated with surgery. The condition occurred without any underlying systemic disease, highlighting the importance of interdisciplinary diagnosis.

    Keywords:
    ocular amyloidosispalpebral massplastic surgery of conjunctiva

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    Area of Science:

    • Ophthalmology
    • Histopathology
    • Medical Research

    Background:

    • Eyelid masses can present as chronic chalazia or hordeola.
    • Amyloidosis is a rare condition characterized by abnormal protein deposits.

    Observation:

    • A 37-year-old male presented with bilateral eyelid masses clinically resembling chronic chalazion and hordeolum.
    • Histopathological examination revealed AL-type amyloidosis with kappa light chain positivity.
    • No systemic disease or monoclonal gammopathy was identified.

    Findings:

    • Surgical excision and reconstruction of the lower eyelids were performed.
    • The patient experienced no recurrence or complications three years post-surgery.
    • Bone marrow biopsy showed a slightly increased number of plasmacytes (up to 10%).

    Implications:

    • This case underscores the rarity of bilateral eyelid amyloidosis without systemic involvement.
    • It emphasizes the critical role of interdisciplinary collaboration in diagnosing and managing such conditions.
    • The successful surgical outcome suggests its efficacy for localized eyelid amyloidosis.