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Updated: Oct 16, 2025

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
Published on: April 20, 2018
Patterns of care for octogenarian patients with head and neck cancer
Muhammad Shahid Iqbal1, Carolina Navarro-Rodriguez2, Sam Munro3
1Department of clinical oncology, Northern Centre for Cancer Care, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, NE7 7DN, United KingdomShahid.iqbal@nhs.net.
Objective:
To examine the patterns of care for octogenarian head and neck cancer patients.
Methods:
All newly diagnosed patients aged 80 years or older, who presented at our centre between June 2018 and October 2020, were included.
Results:
The total number of patients was 42. The median Charlson Comorbidity Index was 5 (range, 4-9). The larynx was the most common subsite (n = 12). Twenty-nine patients (66 per cent) were diagnosed at disease stage IV. Squamous cell carcinoma was the most common histology (86 per cent). Twenty-six patients (62 per cent) had radical treatment and 16 (38 per cent) had palliative treatment. The estimated six-month and one-year overall survival rates for the radical and palliative treatment cohorts were 92.3 per cent and 42.9 per cent (p = 0.001) and 65.4 per cent and 15.4 per cent (p = 0.003), respectively.
Conclusion:
This study provides useful information on octogenarian patients with head and neck cancer. This information may help in conducting prospective studies, especially those focusing on older patients with head and neck cancer, in order to define the ideal care of this patient population.
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