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Normative data for ages 18-45 for ocular motor and vestibular testing using eye tracking.
Aura Kullmann1, Robin C Ashmore1, Alexandr Braverman2
1Neurolign USA LLC, A Subsidiary of Neurolign Technologies Inc. (formerly Neuro Kinetics, Inc.) Pittsburgh Pennsylvania USA.
Laryngoscope Investigative Otolaryngology
|October 20, 2021
Summary
This study establishes normative eye movement data for clinical use in diagnosing vestibular and neurological conditions, including mild traumatic brain injury (mTBI). The findings provide essential reference ranges for eye tracking assessments, aiding patient diagnosis and treatment.
Area of Science:
- Neuroscience
- Ophthalmology
- Vestibular Science
Background:
- Eye tracking is crucial for assessing ocular motor and vestibular function in neurological conditions like TBI.
- Current clinical use is hindered by a lack of normative data for eye movement assessments.
- Diagnostic tests involve visual and motion stimuli to record eye movements.
Purpose of the Study:
- To establish normative reference ranges for eye movement tests.
- To facilitate comparison of patient results with established norms.
- To support clinical diagnosis and treatment of vestibular and neurological disorders.
Main Methods:
- Administered optokinetic response, subjective visual horizontal/vertical, and rotation tests to healthy adults (18-45).
- Utilized rotatory chair or virtual reality goggles with video-oculography for data collection.
- Collected data from 290-449 participants, analyzing gender and age group effects.
Main Results:
- Established 95% reference intervals (RI) for eye movement metrics.
- Found no significant effect of gender or age (pediatric vs. adult) on test results.
- Pooled data and presented RIs with 90% confidence intervals.
Conclusions:
- The developed normative database aids in diagnosing and managing vestibular and neurological conditions, including mild TBI.
- This FDA-cleared database is suitable for clinical practice.
- Provides a valuable tool for treatment and rehabilitation protocols.
