Thromboelastography profiles for controlled circulatory death donors: Validating the role of heparin

W Christian Crannell1, Mitch Sally2, Keeley McConnell2

  • 1Department of Surgery, Division of Abdominal Organ Transplantation, Oregon Health & Science University, Portland, Oregon, USA.

Clinical Transplantation
|October 20, 2021
PubMed

Controlled donation after circulatory death (cDCD) liver transplants are associated with increased ischemic-type biliary complications. Microvascular thrombosis secondary to decreased donor fibrinolysis may contribute to bile duct injury. We hypothesized that cDCD donors are hypercoagulable with impaired fibrinolysis and aim to use thromboelastography to characterize cDCD coagulation profiles.