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Updated: Oct 16, 2025

Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression
Published on: January 12, 2024
[Modern concepts of pathogenesis of diabetic retinopathy]
V M Filippov1, D V Petrachkov1, M V Budzinskaya1
1Research Institute of Eye Diseases, Moscow, Russia.
Abstract:
This literature review presents modern view on the pathogenesis of diabetic retinopathy (DR) paying particular attention to the molecular mechanisms leading to its development, as well as the manifestations of retinal neurodegeneration in such patients. Assessment of this condition and its clinical manifestations makes it possible to diagnose DR at the stage of absent initial vascular changes. Investigating the neurodegeneration mechanisms could supplement the existing understanding of the disease pathogenesis and could possibly help find new ways of treatment and prevention of DR.
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