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Heart failure as a serious complication of iodinated contrast-induced hyperthyroidism: case-report

Sofie M Diepenbroek1,2, A de Jonghe3, C van Rees3

  • 1Department of Geriatrics, Tergooi Medical Centre, Blaricum, The Netherlands. s.m.diepenbroek@gmail.com.

BMC Endocrine Disorders
|October 21, 2021
PubMed

Insights

Iodinated contrast media (ICM) can trigger hyperthyroidism, a rare but serious condition. Close monitoring of elderly patients after ICM exposure is crucial to prevent fatal complications.

Area of Science:

  • Radiology
  • Endocrinology
  • Internal Medicine

Background:

  • Iodinated contrast media (ICM) can disrupt thyroid hormone regulation, leading to hyperthyroidism.
  • This condition, though rare, carries severe and potentially fatal consequences.
  • Current guidelines do not mandate pre-procedure thyroid function testing or prophylactic treatment for high-risk individuals.

Observation:

  • An 82-year-old woman developed hyperthyroidism post-chest CT with ICM.
  • She presented with pneumonia and difficult-to-control tachycardia one month after ICM administration.
  • The patient developed heart failure and died from myocardial ischemia due to the combined effects of hyperthyroidism and pneumonia.

Findings:

  • ICM-induced hyperthyroidism can precipitate severe cardiovascular events.
  • Elderly patients, particularly those with multinodular goiter, are at higher risk.
  • Prompt recognition and management of hyperthyroidism post-ICM are critical.

Implications:

  • Highlights the need for vigilant monitoring of high-risk patients after ICM administration.
  • Emphasizes clinician awareness regarding the potential for severe hyperthyroidism complications.
  • Suggests careful consideration of ICM use, especially in the elderly population.
Abstract

Keywords:
HyperthyroidismICMIodinated contrast mediaIodine-inducedTachycardia

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