Development of a new highly sensitive serotonin sensor based on green synthesized silver nanoparticle decorated
Maroua Moslah1,2, Zina Fredj1, Chérif Dridi1
1NANOMISENE Laboratory, LR16CRMN01, Centre for Research on Microelectronics and Nanotechnology of Sousse (CRMN), Technopole of Sousse B. P. 334, Sahloul, Sousse 4034, Tunisia. cherif.dridi@crmn.rnrt.tn.
Abstract:
Electrochemical detection of serotonin (5-hydroxytryptamine, 5-HT) is proposed for the first time using a cost-effective and eco-friendly nanocomposite of AgNPs and rGO which is synthesized through an in situ green reduction process using rosemary leaf extract. The synthesized nanocomposite and the elaborate thin layers have been characterized using UV-Vis, FTIR, TEM, and EIS. The sensitivity of the developed sensor was evaluated by differential pulse voltammetry. The peak current measured at a voltage of 420 mV (vs. Ag/AgCl) increased linearly in the 0.1 nM to 100 µM concentration range. A very low limit of detection of 78 pM compared to those in recent studies reported in the literature was obtained. The innovative approach was successfully applied to the determination of serotonin in spiked artificial urine samples.
More Related Videos
11:18Manufacturing of a Nafion-coated, Reduced Graphene Oxide/Polyaniline Chemiresistive Sensor to Monitor pH in Real-time During Microbial Fermentation
Published on: January 7, 2019
03:33Author Spotlight: Development and Application of SERS Flexible Substrates Using Synthesized AgNPs
Published on: November 17, 2023