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Updated: Oct 16, 2025

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Hybrid De Novo Genome Assembly for the Generation of Complete Genomes of Urinary Bacteria using Short- and Long-read Sequencing Technologies
Published on: August 20, 2021
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Democratizing long-read genome assembly
Melanie Kirsche1, Michael C Schatz2
1Department of Computer Science, Johns Hopkins University, Baltimore, MD, USA.
Cell Systems
|October 21, 2021
Abstract:
De novo assembled genomes serve as the backbone for modern genomics. In an article in this issue of Cell Systems, Ekim et al. present the mdBG assembler that can assemble genomes 100-fold faster than previous methods, including a human genome in under 10 min, which unlocks pan-genomics for many species.
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