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Updated: Oct 16, 2025

Reverse Dissection and DiceCT Reveal Otherwise Hidden Data in the Evolution of the Primate Face
Published on: January 7, 2019
Uncovering the HARbingers of human brain evolution
Federica Mosti1, Debra L Silver2
1Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA; Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA.
Abstract:
During evolution, humans acquired extensive genomic changes that collectively define unique features of our species, yet functions for these sequence variants are largely unknown. In this issue of Neuron, Girskis et al. comprehensively screen human accelerated regions (HARs) for enhancer activity in human-specific cortical development, creating a valuable online resource.
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