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Translating the advanced glycation end products (AGEs) knowledge into real-world nutrition strategies
Heitor O Santos1, Nilson Penha-Silva2
1School of Medicine, Uberlandia Federal University (UFU), Uberlândia, Minas Gerais, Brazil. heitoroliveirasantos@gmail.com.
Abstract:
Advanced glycation end products (AGEs) are glycated proteins or lipids derived from complex metabolic pathways involved in the pathophysiology of various diseases, especially diabetes and diabetes-related complications. These compounds are omnipresent in human life, with both endogenous and exogenous sources. Despite the well-elucidated disease mechanisms, little is known about the AGEs/nutrition nexus in the circles of clinical practice recommendations. This review seeks to translate the accumulated knowledge about the biochemistry and pathophysiology of AGEs into a nutritional intervention based on real-world prescriptions.
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