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Epidemiological Features and Predictors of Mortality in Patients with COVID-19 with and without Underlying

Leila Moftakhar1,2, Elahe Piraee2, Mohammad Mohammadi Abnavi2

  • 1Abadan University of Medical Sciences, Abadan, Iran.

International Journal of Hypertension
|October 22, 2021
PubMed

Insights

Individuals with hypertension face a higher risk of COVID-19 mortality. This study highlights hypertension as a significant predictor of death in COVID-19 patients, emphasizing the need for targeted prevention strategies.

Area of Science:

  • Infectious Diseases
  • Cardiovascular Health
  • Epidemiology

Background:

  • Hypertension significantly increases the risk of COVID-19 infection and mortality.
  • Understanding the epidemiological characteristics and mortality predictors in COVID-19 patients with hypertension is crucial.

Purpose of the Study:

  • To assess the epidemiological features of COVID-19 patients with and without hypertension.
  • To identify predictors of mortality in COVID-19 patients, particularly those with hypertension.

Main Methods:

  • Retrospective study comparing COVID-19 patients with (1927) and without (39030) hypertension.
  • Chi-square tests for qualitative variable differences.
  • Logistic regression to determine mortality predictors.

Main Results:

  • Hypertension prevalence in COVID-19 patients was 4.7%, accounting for 24.37% of deaths.
  • Hypertensive COVID-19 patients were older and had more comorbidities (fever, cough, cardiovascular disease, diabetes).
  • Hypertension (3.6x), dyspnea (1.8x), fever (1.25x), cough (1.33x), diabetes (2.21x), and cardiovascular disease (2.2x) were mortality predictors.

Conclusions:

  • Hypertension poses a significant threat to COVID-19 patients, increasing mortality risk.
  • Developing targeted prevention and treatment strategies is essential for managing COVID-19 patients with hypertension and reducing mortality.
Abstract

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