Related Experiment Video
Updated: Oct 16, 2025
The TreadWheel: Interval Training Protocol for Gently Induced Exercise in Drosophila melanogaster
Published on: June 8, 2018
Associations between ACE Genotypes, +8.5 Gz Tolerance, and Body Composition in F-15 Pilot Candidates
1Department of Aero Fitness, Republic of Korea Air Force Academy, Cheongju, Chungbuk 28187, Republic of Korea.
Introduction:
Pilots' +8.5Gz tolerance is related with their selection, safety and special mission suitability. The preliminary study about F-15 pilot candidates were rare, especially related with genetic effect like ACE (angiotensin converting enzyme) gene.
Background:
This study aimed to investigate the associations between the +8.5 Gz test qualification and angiotensin converting enzyme (ACE) genotypes in Korean F-15 pilot candidates for pilot special mission suitability and cadet body composition education.
Materials And Methods:
We performed +8.5Gz test (15 seconds), target gene (ACE) identified and body composition measurements from twenty Korean F-15 pilot candidates (ages 23.0-28.6 years). The +8.5Gz test results (pass and not-passed), body composition parameters and their relationship with the ACE genotype were evaluated.
Results:
Four (20%), six (30%), and 10 (50%) pilots had the DD, DI, and II genotypes based on the ACE gene identification results, respectively. Ten (50%) pilots passed by maintaining consciousness during the +Gz test. Of them, three (75%, 3/4), four (66.7%, 4/6), and three (30%, 3/10) had the DD, DI, and II genotypes (P < .05, DD > II), respectively. Compared with other genotypes, the DD genotype was associated with overall higher values of body composition indices, and this association was more prominent among pilots who passed the +8.5 Gz test.
Discussion:
In some ethnic groups, the DD genotype has been found to have an effect on elite players' high-intensity performance, including muscle power and strength. The DD genotype exhibited the highest performance in terms of passing rate, longest mean breathing interval(s), and higher values of body composition parameters in pilots who passed the +8.5 Gz test.
Conclusions:
In this study, the group with the DD genotype exhibited a higher pass rate and heavier body composition parameters than the group with the II genotype. These results require further investigation to determine their significance and applicability in other ethnic groups.
More Related Videos
05:53Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
Published on: June 21, 2018
09:38Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
Published on: November 14, 2017
Related Concept Videos
01:28Human Genetics
The complex relationship between genetics and psychology is observable through common biological components such...
02:27Background and Environment Affect Phenotype
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
01:18Polygenic Traits
02:41Lethal Alleles
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...
01:17Two-Way ANOVA
The two-way ANOVA analysis initially begins by stating the null hypothesis that there is an interaction effect between the two factors of a dataset. This effect can be visualized using line segments formed by joining the...
01:20Gene-Environment Interactions