Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Antigens Involved in Adaptive Immunity01:26

Antigens Involved in Adaptive Immunity

789
An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and...
789
Cross-reactivity00:42

Cross-reactivity

31.8K
Overview
31.8K
Diversity of Antigen Receptors01:28

Diversity of Antigen Receptors

942
Antigen receptors are essential components of the immune system crucial in defending the body against foreign invaders. These receptors are present on the surface of B and T cells, enabling them to recognize antigens and mount an appropriate immune response.
Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...
942
Antigen Presenting Cells01:22

Antigen Presenting Cells

2.3K
The immune system is a complex network of cells and molecules that protects the body from foreign invaders. T cells, a type of white blood cell, play a crucial role in this process. They recognize and attack foreign substances, such as pathogens, that enter the body.
T cells require the help of antigen-presenting cells (APCs), which process foreign antigens into smaller fragments that can be recognized by T cells. These APCs are highly specialized cells that efficiently internalize antigens...
2.3K
Antigen Processing Pathways01:31

Antigen Processing Pathways

1.5K
MHC molecules are key players in the immune response, enabling T cells to recognize and respond to specific antigens. They are present on the surface of all nucleated cells in the body and are instrumental in presenting antigens to T cells and activating them. T cells recognize the MHC-antigen complex and initiate an immune response. MHC class I and MHC class II are two main types of MHC molecules, each associated with a distinct antigen processing pathway.
MHC Class I: Presenting Endogenous...
1.5K
Antibody Structure01:10

Antibody Structure

61.8K
Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
61.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prediction of Anthracycline Benefit in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Early-Stage Breast Cancer by the MammaPrint 70-Gene Signature for Patients Enrolled in the FLEX Study.

JCO precision oncology·2026
Same author

XAPT: Explainable Anomaly-Driven Prediction of Threat Stages in APT Campaigns.

IEEE access : practical innovations, open solutions·2026
Same author

Disseminating Acute Care for Elders Principles in a Geriatric Observation Unit: Preliminary Data.

Journal of the American Geriatrics Society·2025
Same author

The past, present, and future of anti-idiotype antibodies.

Frontiers in immunology·2025
Same author

Bone mineral density with elagolix plus add-back therapy in women with heavy menstrual bleeding and uterine fibroids: open-label and post-treatment results of a 60-month phase 3 trial.

AJOG global reports·2025
Same author

Semaglutide and diabetic retinopathy: an OHDSI network study.

BMJ open diabetes research & care·2025
Same journal

A Novel Anti-Glypican-3 Monoclonal Antibody G<sub>3</sub>Mab-25 for Versatile Applications.

Monoclonal antibodies in immunodiagnosis and immunotherapy·2026
Same journal

Epitope Mapping of Anti-mouse ACKR4 Monoclonal Antibodies Developed by N-Terminal Peptide Immunization.

Monoclonal antibodies in immunodiagnosis and immunotherapy·2026
Same journal

Epitope Mapping of Anti-Mouse C-C Motif Chemokine Receptor 1 Monoclonal Antibodies Developed by the Cell-Based Immunization and Screening Method.

Monoclonal antibodies in immunodiagnosis and immunotherapy·2026
Same journal

Guidelines for Reporting New Monoclonal Antibodies: Improving Transparency, Reproducibility, and Research Utility.

Monoclonal antibodies in immunodiagnosis and immunotherapy·2026
Same journal

Establishment of a Novel Anti-EphA4 Monoclonal Antibody, Ea<sub>4</sub>Mab-3, for Versatile Applications.

Monoclonal antibodies in immunodiagnosis and immunotherapy·2026
Same journal

Acknowledgment of Reviewers 2025.

Monoclonal antibodies in immunodiagnosis and immunotherapy·2026
See all related articles

Related Experiment Video

Updated: Oct 16, 2025

Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes
08:52

Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes

Published on: July 26, 2019

8.3K

Expert Panel Discussion on Antigenic Sin

Thomas Kieber-Emmons1, Eric Brown2, Peter Nara3

  • 1Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
|October 22, 2021
PubMed
Summary

No abstract available in PubMed .

More Related Videos

Generation of Two-color Antigen Microarrays for the Simultaneous Detection of IgG and IgM Autoantibodies
10:16

Generation of Two-color Antigen Microarrays for the Simultaneous Detection of IgG and IgM Autoantibodies

Published on: September 15, 2016

13.0K
Antigenic Liposomes for Generation of Disease-specific Antibodies
10:31

Antigenic Liposomes for Generation of Disease-specific Antibodies

Published on: October 25, 2018

12.5K

Related Experiment Videos

Last Updated: Oct 16, 2025

Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes
08:52

Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes

Published on: July 26, 2019

8.3K
Generation of Two-color Antigen Microarrays for the Simultaneous Detection of IgG and IgM Autoantibodies
10:16

Generation of Two-color Antigen Microarrays for the Simultaneous Detection of IgG and IgM Autoantibodies

Published on: September 15, 2016

13.0K
Antigenic Liposomes for Generation of Disease-specific Antibodies
10:31

Antigenic Liposomes for Generation of Disease-specific Antibodies

Published on: October 25, 2018

12.5K